WOSCOPS (The West of Scotland Coronary Prevention Study) Sub-study

18 Aug, 10

WOSCOPS (The West of Scotland Coronary Prevention Study) Sub-study

The effects of pravastatin on hospital admission in hypercholesterolemic middle-aged men

Purpose

To determine the effect of lipid lowering with pravastatin on hospital admissions in the WOSCOPS

Design

As per WOSCOPS

Patients

As per WOSCOPS

Follow-up

Mean of 4.9 years

Treatment Regimen

As per WOSCOPS

Results

Overall 2198 (33%) of the 6595 men were admitted to the hospital. There were 4333 admissions and 28% were related to cardiac disease. The number of men requiring hospitalization for cardiovascular causes was reduced by 21% (p = 0.008) in the pravastatin group compared to placebo.
Hospital admissions for cardiac causes per 1000 subject years was decreased by 10.8% (p = 0.0013) in the pravastatin group compared to the placebo group.

Conclusion

Pravastatin decreased hospital admissions for cardiovascular disease in middle aged men with hypercholesterolemia.

J Am Coll Cardiol 1999;33:909-15

Related Topics

hospitalization

hypercholesterolemia