Hey there! Welcome!
Get updated on
Select Speciality
Top Picks
Recent updates in endometriosis management (FOGSI-ICOG) include medical and surgical options. First-line treatments are NSAIDs, combined oral contraceptives (COCs), and progestogens (Dienogest, LNG-IUD). GnRH agonists/antagonists are second-line with add-back therapy. Aromatase inhibitors are third-line for resistant cases. Surgery is for severe or refractory cases, aiming to remove lesions while preserving function.
Nebulization therapy uses jet, ultrasonic, and mesh nebulizers based on drug formulation and patient needs. Bronchodilators, corticosteroids, mucolytics, and antimicrobials are common for ventilated patients. Jet nebulizers are ideal for prolonged treatments with unstable drugs, while ultrasonic nebulizers offer efficient aerosol delivery. Mesh nebulizers provide precise dosing. Proper cleaning is key to safety.
Researchers developed predictive models for diabetic kidney disease (DKD) progression to end-stage renal disease (ESRD) in type 2 diabetes. Key predictors included BMI, eGFR, urinary total protein, and systemic immune-inflammatory index. The combined model of tubular atrophy, interstitial fibrosis, & other factors showed enhanced accuracy with strong predictive ability at 5 years, offering a personalized treatment.
A study on cognitive decline following a first-time transient ischemic attack (TIA) found that, despite symptom resolution, TIA patients experienced a faster rate of annual cognitive decline than asymptomatic controls (−0.05 vs. −0.02). Stroke patients showed more significant cognitive decline both immediately (−0.14) and annually (−0.04), suggesting TIA may cause lasting cognitive effects.
A long-term study involving 14,807 children examined the impact of postnatal antibiotic treatment in full-term infants due to maternal group B streptococcus (GBS) infection & found 1.3 times greater risk of asthma (RR=1.3). Secondary outcomes included increased use of short-acting beta agonists (SABA) & allergic rhinitis, highlighting the role of early-life antibiotics exposure in childhood asthma development.
Salvage low-dose-rate brachytherapy (LDR-BT) offers greater recurrence-free survival (RFS) compared to high-dose-rate brachytherapy (HDR-BT) in radio-recurrent prostate cancer. LDR-BT showed an average RFS of 131.6 months, with 2-, 3-, and 5-year rates of 84.6%, 74.3%, and 63.5%, respectively. However, LDR-BT was linked to higher rates of severe gastrointestinal and genitourinary toxicities compared to HDR-BT.