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12 May, 23
Key session presented at the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 2023, 15-18 April 2023, Copenhagen, Denmark.
Determining longitudinal HbA1c trajectories in T2DM patients may identify those at high-risk of PAH, reported a recent study. Patients with moderate-stable, high-decrease, & high-persistent trajectories vs. those with low-stable trajectory had higher risks of overall PAH, diabetes PAH, acute & chronic PAH. Apt & timely initiation of targeted intensive therapy may improve prognosis of these patients.
A recent report published in the journal of Diabetes Research and Clinical Practice estimated the prevalence of pre-diabetes and diabetes in children and adolescents. Pre-diabetes and diabetes was prevalent in 15.35% and 0.94% of school-age children whereas, among adolescents, the prevalence was 16.18% and 0.56%, respectively.
- Patients with megaloblastic anemia with high-grade fever had mean Hb: 8.15 g/dL, MCV:111 ± 7.8 fL, unconjugated hyperbilirubinemia in 75%, mean LDH:814 ± 24 IU/L, and low B12 or folate levels in 87.5%
- Megaloblastic anemia should be considered as differential diagnosis of fever with negative workup
- Most patients responded to treatment (B12 or folic acid) in 1-5 days and lab parameters improved in 1 week
- 1/3 of dengue cases (33%) presented with PE and it was significantly higher in children (43%) and in patients with complicated infection (48%)
- Lung ultrasound more often detected PE compared to chest X-ray (38% vs. 28%)
- PE is a relatively common complication in dengue; bedside imaging tools like lung ultrasound may enhance detection and assess severity
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