OSCAR

14 Dec, 10

OSCAR

Objective

To compare the effect of rosuvastatin with high dose atorvastatin on lipid and anti-inflammatory parameters in patients undergoing coronary stenting for non ST-elevation acute coronary syndrome (NSTE ACS).

Patient Profile

138 consecutive patients who underwent successful coronary stenting for NSTE ACS

Study Design

The discharged patients, in addition to dual anti-platelet therapy were randomized 1:1 to receive rosuvastatin 20 mg or atorvastatin 80 mg.
Clinical follow-up was done 1 month after hospital discharge.

Results

Patients receiving rosuvastatin 20 mg and atorvastatin 80 mg showed no differences for LDL-C, patients attaining LDL-C goals, HDL-C and hs-CRP.

Conclusion

After coronary stenting for NSTE ACS, rosuvastatin 20 mg and atorvastatin 80 mg have similar effects on lipid and anti-inflammatory parameters.

Published online in Thrombosis Research 2010.