AOCCN 2025: Electroencephalographic Abnormalities in Children with Autism Spectrum Disorder: Clinical Correlates and Comorbidities

Presenter: Dr. Anmol Gupta

This retrospective study examined electroencephalographic (EEG) abnormalities in children with Autism Spectrum Disorder (ASD) and their clinical correlates.

Records of 20 children (mean age 8.6 years) from a cohort of 168 ASD cases were analyzed. EEG abnormalities were present in 20%, predominantly generalized epileptiform discharges and parietal-occipital focal changes. Abnormal EEGs were strongly associated with epilepsy (85%) and intellectual disability (78%). Children with severe autism (CARS2 >37) showed higher abnormality rates, alongside a nonsignificant trend toward lower IQ. Findings suggest EEG abnormalities are common in ASD with comorbidities particularly in those with comorbid epilepsy and intellectual disability, highlighting EEG’s utility in neurodevelopmental evaluation. Larger prospective studies are needed.

AOCCN 2025, September 17th-20th 2025, New Delhi, India.