Excess weight affects women’s fertility and pregnancy outcomes, raising risks of miscarriage, stillbirth, GDM, hypertension, and PPH. Later in life, it increases cardiovascular, cancer, diabetes, and liver disease risks. Breastfeeding reduces postpartum weight and chronic disease. FIGO guidelines and nutrition checklists support health professionals in managing weight-related health impacts across women’s lifespans.

In 701 DPP participants with T2D, younger-onset was linked to higher FPG, BMI, DBP, lower HDL, smaller BP/lipid improvements, and rising HbA1c over 7.9 years. Older-onset had higher SBP, lower eGFR, and stable glycaemia. Younger-onset were more often on glucose-lowering drugs. Findings highlight worse metabolic progression in early-onset T2D despite better renal and BP profiles.

Recent NHANES data showed that adults with rheumatoid arthritis (RA) have a higher prevalence of kidney stones than those without RA (17.0% vs. 8.1%). RA was associated with 77% elevated odds of kidney stones (OR 1.77), post adjusting for demographic, metabolic, and lifestyle factors. This relationship held consistent across all subgroups.

Neutrophil-to-lymphocyte ratio (NLR >4.8) was a robust predictor of worse outcomes in patients with localized cutaneous melanoma (stage I-II), found a study. Higher NLR corresponded to poorer melanoma-specific survival (HR 3.2) and higher risk of distant metastases (HR 2.0). Elevated NLR was also linked to tumor features like ulceration, higher mitotic index of > 5 mitoses/mm², and head or neck location.

Adults born extremely preterm (≤ 28 weeks) face a four-fold higher risk of major depressive disorder (OR 4.14) and a five-fold higher risk of anxiety disorder (OR 5.17) compared to term births. The depression link weakened after adjusting for maternal smoking and alcohol intake. Childhood emotional and peer-related issues further raised the risk of adult depression among those born preterm.

A 9-year analysis of CHARLS data revealed that sarcopenic adults (≥ 45 years) were at a higher risk of hip fracture than those without it (7.2% vs. 3.8%). Sarcopenia independently raised hip fracture risk by 33% (aOR 1.33), even after adjusting for lifestyle factors and comorbidities. Findings highlight the need for early identification and prevention of sarcopenia to reduce fracture burden.