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RSV continues to pose a significant threat beyond infancy, with toddlers facing high disease burden and acting as key transmitters. Reinfections, long-term respiratory effects, and limited vaccine coverage highlight the need for extended protection. Strengthening early mucosal immunity—especially IgA responses—is essential to prevent infection and reduce RSV transmission in this age group.
A Greek cohort study found that inappropriate empirical therapy in pediatric UTIs was linked to higher rates of ESBL pathogens, renal scarring, and prolonged hospital stays. Though most cases had favorable outcomes, timely pathogen identification and antibiogram-guided treatment are essential to prevent complications and improve care quality.
A study of stage 3–5 non-dialysis-dependent chronic kidney disease (NDD-CKD) patients found rising magnesium imbalance with CKD progression. Hypomagnesemia increased from 0% (G3) to 15.1% (G5), and hypermagnesemia from 5.1% to 30.1%. Serum magnesium correlated positively with calcium and the calcium-phosphorus product, highlighting its potential role in CKD-related mineral-bone disorder.
In 1,148 elderly obstructive sleep apnea patients, 24% had probable sarcopenia. The triglyceride-glucose (TyG) index was an independent predictor (odds ratio >2.0) with a cutoff of 8.855 (67.4% sensitivity, 62.8% specificity; AUC 65.7%). These findings spotlight TyG as a potential metabolic marker for early muscle health assessment in older adults with OSA.
Among 1,95,195 atrial fibrillation (AF) patients, 13% developed diabetes over 6 years. In these AF patients, steatotic liver disease (SLD) raised risk of diabetes (HR 1.93 in metabolic dysfunction-associated SLD, HR 1.79 in metabolic dysfunction and alcohol-related ALD & HR 1.93 in alcohol-related LD). In those aged 20–39, risk surged over 5-fold. Findings stress early metabolic screening in AF patients with SLD.
In 27,113 diabetics with severe chronic kidney disease (CKD), an HbA1c range of 6.7–7.1% was linked to the lowest risk of complications in a recent study. Major adverse cardiovascular events increased at HbA1c ≥7.2% & <5.8%, while hypoglycemia-related hospitalizations increased at ≥6.7%. An HbA1c range of 6.7–7.1% may be most favorable for lowering long-term complications in this subgroup of patients.
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