Key session presented at the European Academy of Dermatology and Venereology (EADV) Congress 2024, 25-28th September 2024, Amsterdam, Netherlands

Key session presented at the European Academy of Dermatology and Venereology (EADV) Congress 2024, 25-28th September 2024, Amsterdam, Netherlands

The 40-year follow-up of the Framingham Heart Study found that high scores on the Framingham Stroke Risk Profile (FSRP) significantly increased the risk of developing all-cause dementia & Alzheimer's disease (AD). Alarmingly, women faced a 2.81-fold increased risk for dementia and a 2.96-fold increase for AD, while men did not show a similar association. Diabetes & high SBP emerged as critical risk factors for women.

Mothers with HS faced a 30%-60% higher likelihood of serious complications, such as hypertensive disorders, GDM & severe maternal morbidity, found a 16-yr study involving 1.3 million pregnant women. In addition to the increased risks of preterm birth & birth defects in their offspring, these women had up to 2.5 times the risk of long-term health issues, including metabolic & infectious conditions, after childbirth.

Changes in the Fibrosis-4 score correlated with liver stiffness measurements in patients with metabolic dysfunction-associated steatotic liver disease (MASLD). However, the strongest predictors of significant fibrosis were found to be comorbid diabetes mellitus (OR 2.43), obesity (OR 3.88), and baseline ALT ≥ 30 (OR 8.55). Monitoring this may be more crucial in predicting liver fibrosis progression in MASLD patients.