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    20 Mar, 2019
    Sustained systolic blood pressure (SBP) control may be beneficial for preventing stroke, heart failure (HF), and cardiovascular disease (CVD) outcomes in adults taking antihypertensive medication, revealed a recent study. According to the findings of the study, patients with a sustained SBP (<140 mmHg) at less than 50% clinic visits were more likely to suffer with stroke, HF and CVD as... Read more
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    20 Mar, 2019
    A post-hoc analysis of the Lung Volume Reduction Coil Treatment in Patients With Emphysema (RENEW) trial identified baseline predictors, including quantitative CT (QCT) measures, that defined a patient subgroup most likely to benefit from endobronchial coil therapy. Patients selected for lobar volume reduction with endobronchial coil therapy should meet the following 3 criteria- 1. Significant... Read more
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    20 Mar, 2019
    Omalizumab is a monoclonal IgE antibody which is used in patients with chronic spontaneous urticaria (CSU) resistant to conventional drugs.  These patients typically have low serum dehydroepiandrosterone sulphate (DHEA-S) levels.  Recently researchers studied the effect of omalizumab treatment on serum DHEA-S levels and its correlation with the remission and relapse times of CSU. The... Read more
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    20 Mar, 2019
    A recent retrospective study concluded that androgen deprivation therapy (ADT) for ≥2 years significantly increases the risk of mortality due to causes other than prostate cancer (PCa), especially in localized PCa patients aged ≥75 years. The impact of ADT on other-cause of mortality (OCM) was evaluated in 1125 patients with localized PCa and treated with modern high-dose radiotherapy,... Read more
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    20 Mar, 2019
    A recent study investigated various inflammatory mediators according to different nasal tissues in chronic rhinosinusitis (CRS) and compared them within the same subject. The results demonstrated distinct immunologic profiles among the subtypes of CRS. Increased Th2 immune response was observed in the nasal polyp (NP) tissues as compared to uncinate process mucosa (UP), irrespective of CRS with... Read more
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    19 Mar, 2019
    A recent study examined pediatric patients operated for appendicitis to understand the microbial overlap between intraoperative and abscess cultures, and antibiotic resistance patterns. The study showed that microbial overlap between intraoperative cultures and intraabdominal abscesses (IAA) cultures was limited and only 29% (10/35) of patients having some overlap in cultured organisms.... Read more
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    18 Mar, 2019
    Albuminuria and urinary N-acetyl-β-D-glucosaminidase (uNAG) are established markers for progression of diabetic kidney disease. But little is known about the association between urinary non-albumin proteinuria (NAP) and uNAG and their clinical relevance in patients without albuminuria. A recent study that elucidated this link, revealed a moderate correlation between NAP and uNAG. Furthermore, NAP... Read more
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    18 Mar, 2019
    Montelukast effectively reduced the nasal and ocular symptoms in patients with nonallergic rhinitis eosinophilic syndrome (NARES) and asthma, reported a recent study. Treatment with montelukast improved the patient-reported outcomes (PROs) such as olfactory dysfunction and night-time disturbances and reduced the nasal mucosal eosinophil filtration and biomarkers, added the authors. The study... Read more
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    15 Mar, 2019
    Surgery for endometriosis may involve several organs (vagina, uterus, ovary) and sometimes may involve opening of intestinal tract. Evidence reporting the surgical site infection (SSI) after surgery for endometriosis is scarce. To decide the most appropriate treatment strategy among these patients, it is important to have knowledge regarding the rate of SSI after surgery for endometriosis.... Read more
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    15 Mar, 2019
    In a recent retrospective, open cohort study researchers studied the effect of glycaemic control on fracture risk in people with newly diagnosed Type 1 diabetes.  Findings revealed that in people with newly diagnosed type 1 diabetes, fracture risk increased by 7% for each percentage increase in HbA1c. Researchers noted that patients with HbA1c values of > 74.9 mmol/mol (> 9%) had 23 %... Read more
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    15 Mar, 2019
    Rheumatoid arthritis (RA) treatment generally includes conventional (cs), biologic (b) disease-modifying anti-rheumatic drugs (DMARDs) with or without concomitant glucocorticoids (GCs). In cases where disease activity is not controlled under csDMARD treatment, targeted synthetic (ts) or bDMARDs are added to treatment. In a recent study, researchers hypothesized that treat-to-target (T2T) strategy... Read more
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    15 Mar, 2019
    A recent study conducted in Africa, underscored the importance of considering more foot-specific parameters for identifying the risk of diabetic foot ulcers (DFU) in diabetes patients. According to the findings of the study, diabetes patients with DFU exhibited certain distinct characteristics with regards to foot related parameters. These included; swollen foot, limited ankle mobility, and... Read more
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    14 Mar, 2019
    Although laparoscopic appendectomy is considered safe, there is a risk of intra-abdominal abscesses (IAA) complication, which has an incidence of 2.2%. Irrigation during appendectomy is one of the factors that affects the development of IAA but there is no clear consensus on the effect of irrigation on the rate of IAA. A recent meta-analysis investigated current evidence regarding the role of... Read more
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    14 Mar, 2019
    Anticoagulant therapy (AT) did not have an impact on the overall orthotopic liver transplant (OLT)-free survival in patients with cirrhosis and portal vein thrombosis (PVT), concluded a recent study. However, AT resulted in a significantly higher OLT-free survival in advanced cirrhosis such as patients with Child-Pugh B or C or having model end stage liver disease (MELD) score >15. The authors... Read more
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    14 Mar, 2019
    This was the first study which demonstrated a strong association between the pollen count on the day of polysomnography (PSG) and the severity of sleep disordered breathing (SDB) in children with allergic rhinitis (AR). Additionally, grass pollen was identified as the strongest determinant of all the respiratory parameters used to assess the SDB severity by physicians. The researchers of this... Read more