• 0
    27 Mar, 2020
    Postprandial glycemia is a known risk factor for diabetes and cardiovascular disease. A recent study demonstrated that the sequence of food consumption with rice based meal had a significant impact on postprandial glucose, insulin and incretin response without affecting satiety in healthy individuals. Eating vegetables and protein before carbohydrate is a simple and novel eating strategy to curb... Read more
  • 0
    27 Mar, 2020
    A first-of-its kind study conducted in pediatric patients demonstrated that children with epilepsy and with acquired demyelinating disorders of the central nervous system (CNS) had significantly higher serum α-synuclein levels as compared with their healthy counterparts. Importantly, these increased α-synuclein levels correlated with measures of disease severity. The study further reported serum... Read more
  • 0
    26 Mar, 2020
    The impact of antihypertensive combination therapy on the risk of hypokalemia is unclear as of now. A recent study revealed hypokalemia to be a common finding in hypertensive patients treated with combinations of various antihypertensive medications. Patients who received thiazide diuretics in combination with calcium channel blockers (CCB), renin angiotensin system inhibitors (RASi), or beta-... Read more
  • 0
    26 Mar, 2020
    A simple magnetic resonance imaging (MRI) score based on visual rating can be used in routine clinical practice to predict the risk of dementia and cognitive decline for patients with cerebral small vessel disease (SVD), reported a large-scale study. Researchers ascertained whether a simple score based on rapid visual assessment of clinical MRI scans would predict the risk of cognitive decline... Read more
  • 0
    24 Mar, 2020
    The existing data with respect to prenatal antibiotic exposure and mode of delivery increasing the risk of wheezing in infants and toddlers are varying. A recent study suggested that children born by Cesarean sections may be more susceptible to infectious wheezing. The study however, found no association between prenatal antibiotic exposure and wheezing types. This study was conducted to... Read more
  • 0
    20 Mar, 2020
    Late-onset sepsis due to coagulase-negative staphylococci (CoNS) is frequent in preterm infants. Although vancomycin is the first-line therapy, emergence of vancomycin-resistant strains has led to increased use of linezolid. Nevertheless, currently little is known about the long-term safety of linezolid in preterm infants.  A recent study revealed that linezolid exposure did not... Read more
  • 0
    20 Mar, 2020
    With the increasing use of continuous glucose monitoring (CGM), time in range (TIR) and other CGM metrics have now emerged as the core metrics for clinical targets and assessing diabetic complications, beyond glycosylated haemoglobin (HbA1c). A recent study demonstrated that amongst type-2 diabetes mellitus (T2DM) patients, TIR 70-180 mg/dL and... Read more
  • 0
    20 Mar, 2020
    It is not known whether discontinuation of renin-angiotensin system blockade when estimated glomerular filtration rate (eGFR) falls below 30 mL/min/1.73 m2 is linked to the risk of all-cause mortality, major adverse cardiovascular events (MACE), and end-stage kidney disease (ESKD) in the subsequent 5 years.  A recent large-scale real-world study demonstrated that discontinuation of... Read more
  • 0
    20 Mar, 2020
    Various ophthalmologic symptoms are frequent yet under-reported in Parkinson’s disease patients. Majority of these visual impairments are treatable hence their timely recognition is crucial amongst PD patients. A recent study reaffirmed a higher prevalence of ophthalmologic symptoms in PD patients as compared to controls. Importantly, the ophthalmologic symptoms interfered considerably in... Read more
  • 0
    20 Mar, 2020
    Majority of acute coronary syndrome (ACS) patients are prescribed beta-blockers (BBs) at discharge. A recent study with an exceptionally long-term follow-up period demonstrated that the adherence to various secondary prevention medications including BBs decreases drastically over the years. Patients who were non-adherent to BBs had an increased risk of long-term mortality that extended... Read more
  • 0
    18 Mar, 2020
    Researchers recently developed a Neuro R2 score to predict the risk of rehospitalization, particularly in patients with neurologic disorders. The risk of rehospitalization was high amongst patients with high Charlson disease count, those requiring urgent/emergent readmission, discharged to rehabilitation or skilled nursing facility, and those suffering with cancer, brain tumor or... Read more
  • 2.5
    17 Mar, 2020
    A recent study demonstrated that adults with early onset (age; 21-44 years) of type-2 diabetes mellitus (T2DM) were less likely to achieve glycemic control at one year following diagnosis. Tailored care approaches are warranted to improve outcomes in these high-risk patients to keep T2DM-associated complications at bay, concluded the researchers. The prevalence of T2DM among adults under age 45... Read more
  • 0
    16 Mar, 2020
    Retrograde intrarenal surgery (RIRS) or percutaneous nephrolithotomy (PCNL) was found to be effective in achieving stone-free status over a short period and minimal number of sessions in the management of lower pole stones (LPS) between 1-2cm. RIRS was more effective than shock wave lithotripsy (SWL) in case of stones smaller than 10mm, concluded a recent systematic review and meta-analysis. The... Read more
  • 0
    16 Mar, 2020
    Secondary prevention of acute myocardial infarction (AMI) is crucial following percutaneous coronary intervention (PCI) in ST-segment elevation myocardial infarction (STEMI) patients. A recent study demonstrated elderly STEMI patients who receive high rather than low dose of statins after PCI had lower level of creatinine kinase-MB (CK-MB), B-type natriuretic peptide (BNP), alanine transaminase (... Read more
  • 0
    16 Mar, 2020
    A cross-sectional study concluded that increased transitional zonal index (TZI) was significantly associated with decreasedinternational index of erectile function (IIEF) score and lower peak systolic velocity (PSV) in men with benign prostatic hyperplasia (BPH).The study analysed the correlation between prostate zonal volume and erectile dysfunction (ED) in patients with BPH. A total of 70 men... Read more