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4 Nov, 25
WHO SE Asia’s Dengue Case Management booklet guides frontline care with protocols for early detection, fluid management, and referrals. It supports primary and home care with tools like monitoring charts and outbreak strategies for resource-limited settings.
4 Nov, 25
This FIGO’s statement highlights HPV vaccination's role to eliminate cervical cancer, emphasizing early immunization, single-dose efficacy, safety, and equitable access to meet WHO’s 90% coverage target by age 15.
5 Nov, 25
Indian J Endocrinol ...
- In the 34–44-week PIONEER REAL India study (N=388), oral semaglutide reduced HbA1c by −1.78% (P<0.0001) and body weight by −7.23 kg (P<0.0001)
- By the end of the study, 34.2% of the patients achieved HbA1c <7%
- Greater HbA1c reduction was seen in those with baseline >9% (−2.48%) vs ≤9% (−0.93%)
- No new safety concerns emerged, favoring the decision-making for initiating oral semaglutide in T2DM patients in India.
5 Nov, 25JAMA Cardiol.
- Sleep disordered breathing (SDB) was highly prevalent (59%), yet underdiagnosed in patients with HCM
- SDB was linked to higher LV mass index (128 vs 109 g/m²; P=0.03), E/e′ ratio (12.5 vs 10.0; P=0.04), baseline troponin-T (0.013 vs 0.011 ng/mL; P=0.04), & greater overnight troponin-T rise (0.0021 vs 0.0002 ng/mL; P=0.02)
- SDB was associated with worse NYHA class, hypertension, & diabetes.
4 Nov, 25BMC Pediatr.
- A high prevalence of vitamin A deficiency (VAD) was reported in pediatric sepsis vs. controls (61.7% vs. 20%; P<0.001)
- VAD correlated with higher PRISM scores, greater sepsis severity, and longer pediatric ICU stays
- Serum vitamin A levels ≤21.4 µg/dl predicted sepsis in children (AUC 0.699, P<0.001)
- VAD was frequent in non-survivors (71.4%); no correlation seen with mortality.
4 Nov, 25Open Forum Infect Di...
- In ICU patients, polymicrobial bloodstream infections were linked to similar risk of 90-day mortality versus monomicrobial ones(31.1% vs. 28.3%; not significant)
- No major differences were found in other outcomes of all-cause 30-day mortality, microbiological failure, initiation of extracorporeal membrane oxygenation, acute respiratory distress syndrome, fever or hospital stay.
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